查看狗狗原发性心脏血管肉瘤的流行病学、临床和病理特征:51例的回顾的源代码
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狗狗原发性心脏血管肉瘤的流行病学、临床和病理特征:51例的回顾
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== 摘要 (Abstract) == 在此介绍的研究中,我们旨在描述 51 例经组织学证实诊断为原发性心脏血管肉瘤 (HSA) 的犬类病例的流行病学、临床和病理学发现。检查每只狗的医疗数据,包括信号、主诉、体格检查结果、各种诊断测试的结果和治疗方法。此外,对所有51例病例进行了病理复查。肿瘤最常发生在年长的金毛猎犬中,其次是马耳他犬和微型腊肠犬。HSA的占位性病变更常见于右耳廓(RAu)(25/51)和右心房(RA)(21/51),RA肿块明显大于RAu肿块(P<0.001)。RAu组肿块的超声心动图检出率(60%;15/25)明显低于RA组(95%;20/21)。5只在肿瘤切除后接受辅助化疗的狗的生存时间(P<0.05)明显长于12只未接受辅助化疗的狗。在这个系列中,马耳他犬 (9/51) 和微型腊肠犬 (7/51) 以及金毛猎犬比其他品种更频繁地出现。与RA肿块相比,RAu肿块的超声心动图检出率较低,这可能与肿瘤大小和/或位置有关。接受辅助化疗的狗的生存时间明显更长,这表明术后化疗可能对患有心脏 HSA 的狗有用。 In the study presented here, we aimed to describe the epidemiological, clinical and pathological findings of 51 canine cases with histologically-verified diagnoses of primary cardiac hemangiosarcoma (HSA). The medical data for each dog, including signalment, presenting complaints, physical examination findings, results of various diagnostic testing performed and method of treatment, were checked. In addition, all 51 cases were re-examined pathologically. The tumor occurred most frequently in older Golden Retrievers, followed by Maltese dogs and Miniature Dachshunds. Mass lesions of HSA were found more commonly in the right auricle (RAu) (25/51) and right atrium (RA) (21/51), and the RA masses were significantly (P<0.001) larger than the RAu masses. The echocardiographic detection rate of masses in the RAu group (60%; 15/25) was significantly lower than that in the RA group (95%; 20/21). Survival time was significantly (P<0.05) longer for 5 dogs that received adjuvant chemotherapy after tumor resection than for 12 dogs that did not. In this series, the Maltese (9/51) and Miniature Dachshund (7/51), as well as the Golden Retriever, were represented more frequently than other breeds. The lower echocardiographic detection rate of RAu masses compared with RA masses may be related to tumor size and/or location. The significantly longer survival time for dogs receiving adjuvant chemotherapy indicates that postoperative chemotherapy could be useful for dogs with cardiac HSA. <br>
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