查看基于多柔比星的化疗对右心房肿块和心包积液狗的回顾性评估的源代码
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基于多柔比星的化疗对右心房肿块和心包积液狗的回顾性评估
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=== Case selection === 对美国洛杉矶周边四家小动物专科医院(高级兽医护理中心、VCA 西洛杉矶动物医院、洛杉矶高级重症监护和奥兰治县兽医癌症小组)的病历数据库进行了审查,以寻找超声心动图识别出 RA 肿块和 PE 的狗。必须通过超声心动图识别源自右心房、RA 附属物或右房室 (AV) 沟的肿块才能纳入研究。超声心动图必须由董事会认证的心脏病专家或心脏病学住院医师在董事会认证的心脏病专家的监督下进行。由于对生存的潜在影响,对 RA 肿块进行任何手术(包括心包切除术或肿块切除术)的狗被排除在外(Kersetetter 等人,1997 年,Weisse 等人,2005 年)。未接受多柔比星作为化疗方案一部分的狗也被排除在研究之外。从病历中收集的数据包括信号、临床体征、体格检查结果、诊断测试结果和长期生存率。当病历中没有长期存活记录时,会向转诊兽医或狗的主人拨打后续电话。生存数据从超声心动图确定 RA 肿块后出院之日开始计算。 The medical record database from four small animal specialty hospitals (Advanced Veterinary Care Center, VCA West Los Angeles Animal Hospital, Advanced Critical Care of Los Angeles and Veterinary Cancer Group of Orange County) around Los Angeles in the USA was reviewed for dogs that had echocardiographically identified RA masses and PE. A mass originating from the right atrium, RA appendage or right atrioventricular (AV) groove had to be identified echocardiographically for inclusion in the study. The echocardiogram had to have been performed by a board-certified cardiologist or a cardiology resident under supervision of a board-certified cardiologist. Dogs that had any surgery for the RA mass including pericardiectomy or mass resection were excluded owing to the potential effect on survival (Kersetetter et al. 1997, Weisse et al. 2005). Dogs that did not receive doxorubicin as part of their chemotherapy protocol were also excluded from the study. Data collected from the medical record included signalment, clinical signs, physical examination findings, diagnostic test results and long-term survival. When long-term survival was not available in the medical record, follow-up phone calls were made to the referring veterinarian or to the owner of the dog. Survival data were calculated from the date of discharge from the hospital after identification of the RA mass on echocardiography. <br>
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