查看狗狗原发性心脏血管肉瘤的流行病学、临床和病理特征：51例的回顾的源代码

===  动物 (Animals) ===

在 2002 年至 2011 年期间，有 55 只原发性心脏 HSA 被临床诊断为原发性心脏 HSA 的狗狗被送往东京农业技术大学兽医临床肿瘤学系进行尸检。其中四只在诊断时未经治疗就被安乐死的狗被排除在外，剩下 51 只狗作为研究材料（表 1）。每只狗的医疗数据包括信号、主诉、体格检查结果、各种诊断测试的结果和治疗方法。所有 51 只狗都死于与 PE 或心脏 HSA 转移有关的原因。常见的主诉包括嗜睡（35 只狗）、虚弱（29 只）、运动不耐受（28 只）、厌食症（22 只）、呼吸困难和咳嗽（18 只）、虚脱（15 只）和体重减轻（12 只）。体格检查的常见异常包括心音低沉（36 只狗）、粘膜苍白（27 只）、心动过速（24 只）、股动脉搏动减弱（17 只）、呼吸用力增加（14 只）、颈静脉扩张（11 只）和腹胀（6 只）。所有 51 例病例在初次就诊时均进行全血细胞计数和血清生化分析。19 只狗的 CBC 结果正常；其余 32 只狗患有轻度贫血 （21）、轻度白细胞增多 （15） 或两者兼而有之 （4）。血清生化参数一般在正常范围内，但血尿素氮浓度（18）和血清谷氨酸丙酮酸转氨酶活性（11）轻度升高。

During the period 2002 to 2011, 55 dogs in which primary cardiac HSA had been diagnosed clinically were submitted to the Department of Veterinary Clinical Oncology, Tokyo University of Agriculture and Technology, for postmortem examination. Four of the dogs, which had been euthanatized without treatment at the time of diagnosis, were excluded, leaving 51 dogs as the study materials (Table 1). The medical data obtained for each dog included signalment, presenting complaints, findings of physical examination, results of various diagnostic tests and method of treatment. All 51 dogs died of causes related to PE or metastasis from cardiac HSA. Common presenting complaints included lethargy (35 dogs), weakness (29), exercise intolerance (28), anorexia (22), dyspnea and cough (18), collapse (15) and weight loss (12). Common abnormalities on physical examination included muffled heart sounds (36 dogs), pale mucous membranes (27), tachycardia (24), weak femoral pulses (17), increased respiratory effort (14), jugular distention (11) and abdominal distention (6). CBCs and serum biochemical analyses were performed at initial presentation in all 51 cases. Results of CBCs were normal for 19 dogs; the remaining 32 dogs had mild anemia (21), mild leukocytosis (15) or both (4). Serum biochemistry parameters were generally within the normal ranges, although mild increases in the blood urea nitrogen concentration (18) and serum glutamic pyruvic transaminase activity (11) were noted.

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