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== The glutamate system and addiction ==

谷氨酸系统和成瘾

* Addiction involves enduring neuroplasticity in the reward  circuitry of the brain.
* Neuroplasticity is a result of glutamate-dependent long-term potentiation.
* Glutamate is an excitatory neurotransmitter.
* Glutamate release is involved in alcohol and drug relapse in response to drug cues.
* There are changes in glutamate receptor functioning in  substance addiction.
* Medications that reduce glutamate tone may prevent alcohol and drug relapse

 • 成瘾涉及大脑奖励回路中持久的神经可塑性。
 • 神经可塑性是谷氨酸依赖长期增强的结果。
 • 谷氨酸是一种兴奋性神经递质。
 • 谷氨酸的释放与酒精和药物复发有关。
 • 物质成瘾中谷氨酸受体功能发生变化。
 • 降低谷氨酸调理的药物可以防止酒精和药物复发

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