2011.PE
(以“== 摘要 == <br> == 讨论 == 在人类医学中，抗凝剂（如华法林）已被用于预防和治疗冠状动脉疾病，以前的报道描述了与这种...”为内容创建页面) |
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| + | In human medicine, anticoagulants, such as warfarin, have been used for prevention and therapy of coronary artery diseases and previous reports have described the development of pericardial effusions associated with this anticoagulation therapy in humans (8–10). Despite strong evidence favoring a causative role of anticoagulation in the genesis of late cardiac tamponade from intrapericardial bleeding (11,12), there is not a clear answer to the question of whether anticoagulant treatment promotes development of pericardial effusion (13). | ||
| + | Cardiac biomarkers (cTnI and CK-MB) were significantly increased in this dog. According to the study by Shaw et al (14), dogs with pericardial effusion had significantly higher serum levels of cTnI than did normal dogs. Dogs with hemangiosarcoma had much higher concentrations of cTnI (2.77 ng/dL; range: 0.09 to 47.18 ng/dL) than did dogs with idiopathic pericardial effusion (0.05 ng/dL; range: 0.03 to 0.09 ng/dL)(P , 0.001) (14). Our data were similar to the values obtained | ||
在人类医学中，抗凝剂（如华法林）已被用于预防和治疗冠状动脉疾病，以前的报道描述了与这种抗凝治疗相关的人类心包积液的发展 （8–10）。尽管有强有力的证据表明抗凝治疗在心包内出血导致晚期心包填塞的发生中具有致病作用 （11,12），但对于抗凝治疗是否促进心包积液发展的问题尚无明确的答案 （13）。 | 在人类医学中，抗凝剂（如华法林）已被用于预防和治疗冠状动脉疾病，以前的报道描述了与这种抗凝治疗相关的人类心包积液的发展 （8–10）。尽管有强有力的证据表明抗凝治疗在心包内出血导致晚期心包填塞的发生中具有致病作用 （11,12），但对于抗凝治疗是否促进心包积液发展的问题尚无明确的答案 （13）。 | ||
2024年6月15日 (六) 12:10的版本
1 摘要
2 讨论
In human medicine, anticoagulants, such as warfarin, have been used for prevention and therapy of coronary artery diseases and previous reports have described the development of pericardial effusions associated with this anticoagulation therapy in humans (8–10). Despite strong evidence favoring a causative role of anticoagulation in the genesis of late cardiac tamponade from intrapericardial bleeding (11,12), there is not a clear answer to the question of whether anticoagulant treatment promotes development of pericardial effusion (13). Cardiac biomarkers (cTnI and CK-MB) were significantly increased in this dog. According to the study by Shaw et al (14), dogs with pericardial effusion had significantly higher serum levels of cTnI than did normal dogs. Dogs with hemangiosarcoma had much higher concentrations of cTnI (2.77 ng/dL; range: 0.09 to 47.18 ng/dL) than did dogs with idiopathic pericardial effusion (0.05 ng/dL; range: 0.03 to 0.09 ng/dL)(P , 0.001) (14). Our data were similar to the values obtained
在人类医学中，抗凝剂（如华法林）已被用于预防和治疗冠状动脉疾病，以前的报道描述了与这种抗凝治疗相关的人类心包积液的发展 （8–10）。尽管有强有力的证据表明抗凝治疗在心包内出血导致晚期心包填塞的发生中具有致病作用 （11,12），但对于抗凝治疗是否促进心包积液发展的问题尚无明确的答案 （13）。 这只狗的心脏生物标志物（cTnI 和 CK-MB）显着增加。根据 Shaw 等人 （14） 的研究，心包积液狗的血清 cTnI 水平明显高于正常狗。血管肉瘤患者的cTnI浓度（2.77 ng/dL;范围：0.09-47.18 ng/dL）远高于特发性心包积液（0.05 ng/dL;范围：0.03-0.09 ng/dL）（P，0.001）（14）。我们的数据与获得的值相似.
