Pharmacology
来自Jack's Lab
蓝皮圣经第 14 版 (2022) 精要
Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, 14th Edition
1 Ch61 Antifungal Agents
抗真菌剂
1.1 Terbinafine
特比萘芬
特比萘芬是一种合成烯丙胺，在结构上类似于外用剂萘替芬（见下面的讨论）。它抑制真菌角鲨烯环氧化酶，从而减少麦角甾醇的生物合成。
Terbinafine is a synthetic allylamine, structurally similar to the topical agent naftifine (see discussion that follows). It inhibits fungal squalene epoxidase and thereby reduces ergosterol biosynthesis.
